Upside, Downside Movers in the Morning
Upside
– $ALEC +58% (global AL050 license brings $100M upfront, up to $1.17B in milestones and extends the cash runway into 2029)
– $PCVX +55% (VAX-31 OPUS-1 pivotal Phase 3 trial met all prespecified primary endpoints with a safety profile comparable to existing vaccines)
– $PTC +36% (agrees to a $205-a-share all-cash takeover valuing its equity at about $22.6B)
– $RXO +23% (agrees to a $5.8B cash-and-stock takeover by $CHRW, implying about $30.25 a share)
– $XP +17%, $BBD +12%, $NU +13%, $ITUB +14%, $PBR +9.4%, $EMBJ +5.4% (Brazil-linked ADRs surge after the right-wing candidate outperformed polls and led first-round presidential voting)
– $ADSK +4.4% (industrial-software M&A read-through from the PTC takeover)
– $VST +3.5% (reported $4.2B federal loan package expected to fund upgrades at three nuclear plants)
Downside
– $CHRW -7.6% ($RXO acquisition requires new debt and a buyback pause while the market weighs execution and integration risk)
– $INTC -3.8% (no clear fresh company catalyst identified as chip shares lag softer technology futures)
– $ALGN -3.1% (no clear fresh company-specific catalysts identified; notable liquid premarket declines)